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L-lysine biosynthesis V

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
2-oxoglutarate + H2O + acetyl-CoA <=> H+ + (R)-2-hydroxybutane-1,2,4-tricarboxylate + CoA 2.3.3.14 homocitrate synthase

[amino-group_carrier_protein]-C-terminal-[gamma-(L-lysyl)-L-glutamate] + 2-oxoglutarate <=> [amino-group_carrier_protein]-C-terminal-[N-(1-carboxy-5-oxopentyl)-L-glutamine] + L-glutamate 2.6.1.118 [amino-group carrier protein]-gamma-(L-lysyl)-L-glutamate aminotransferase

L-2-aminoadipate + 2-oxoglutarate <=> L-glutamate + 2-oxoadipate 2.6.1.39 2-aminoadipate transaminase
2.6.1.7 kynurenine---oxoglutarate transaminase


[amino-group_carrier_protein]-C-terminal-[gamma-(L-lysyl)-L-glutamate] + H2O <=> L-lysine + [amino_group_carrier_protein]-C-terminal-L-glutamate 3.5.1.130 [amino group carrier protein]-lysine hydrolase

L-2-aminoadipate + [amino_group_carrier_protein]-C-terminal-L-glutamate + ATP <=> [amino-group_carrier_protein]-C-terminal-[N-(1,4-dicarboxybutyl)-L-glutamine] + ADP + phosphate + H+ 6.3.2.43 [amino-group carrier protein]---L-2-aminoadipate ligase

[amino-group_carrier_protein]-C-terminal-[N-(1-carboxy-5-oxopentyl)-L-glutamine] + NADP+ + phosphate <=> [amino-group_carrier_protein]-C-terminal-{N-[1-carboxy-5-oxo-5-(phosphooxy)pentyl]-L-glutamine} + NADPH + H+ 1.2.1.103 [amino-group carrier protein]-6-phospho-L-2-aminoadipate reductase

homoisocitrate <=> (Z)-but-1-ene-1,2,4-tricarboxylate + H2O 4.2.1.114 methanogen homoaconitase
4.2.1.36 homoaconitate hydratase


(R)-2-hydroxybutane-1,2,4-tricarboxylate <=> (Z)-but-1-ene-1,2,4-tricarboxylate + H2O 4.2.1
4.2.1.114 methanogen homoaconitase
4.2.1.36 homoaconitate hydratase



[amino-group_carrier_protein]-C-terminal-[N-(1,4-dicarboxybutyl)-L-glutamine] + ATP <=> [amino-group_carrier_protein]-C-terminal-{N-[1-carboxy-5-oxo-5-(phosphooxy)pentyl]-L-glutamine} + ADP 2.7.2.17 [amino-group carrier protein]-L-2-aminoadipate 6-kinase

homoisocitrate + NAD+ <=> 2-oxoadipate + CO2 + NADH 1.1.1.286 isocitrate---homoisocitrate dehydrogenase
1.1.1.42 isocitrate dehydrogenase (NADP+)
1.1.1.87 homoisocitrate dehydrogenase



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