|
|
2-oxoglutarate + H2O + acetyl-CoA <=> H+ + (R)-2-hydroxybutane-1,2,4-tricarboxylate + CoA
|
2.3.3.14
homocitrate synthase
|
–
|
|
BRENDA:
BR44122;
BS321812
KEGG:
R00271
MetaCyc:
HOMOCITRATE-SYNTHASE-RXN
SABIO-RK:
532
|
|
|
|
[amino-group_carrier_protein]-C-terminal-[gamma-(L-lysyl)-L-glutamate] + 2-oxoglutarate <=> [amino-group_carrier_protein]-C-terminal-[N-(1-carboxy-5-oxopentyl)-L-glutamine] + L-glutamate
|
2.6.1.118
[amino-group carrier protein]-gamma-(L-lysyl)-L-glutamate aminotransferase
|
–
|
|
MetaCyc:
RXN-5184
|
|
|
|
L-2-aminoadipate + 2-oxoglutarate <=> L-glutamate + 2-oxoadipate
|
2.6.1.39
2-aminoadipate transaminase
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
–
|
|
BRENDA:
BR47689
KEGG:
R01939
MetaCyc:
2-AMINOADIPATE-AMINOTRANSFERASE-RXN
SABIO-RK:
1992
|
|
|
|
[amino-group_carrier_protein]-C-terminal-[gamma-(L-lysyl)-L-glutamate] + H2O <=> L-lysine + [amino_group_carrier_protein]-C-terminal-L-glutamate
|
3.5.1.130
[amino group carrier protein]-lysine hydrolase
|
–
|
|
MetaCyc:
RXN-5185
|
|
|
|
L-2-aminoadipate + [amino_group_carrier_protein]-C-terminal-L-glutamate + ATP <=> [amino-group_carrier_protein]-C-terminal-[N-(1,4-dicarboxybutyl)-L-glutamine] + ADP + phosphate + H+
|
6.3.2.43
[amino-group carrier protein]---L-2-aminoadipate ligase
|
–
|
|
MetaCyc:
RXN-15002
|
|
|
|
[amino-group_carrier_protein]-C-terminal-[N-(1-carboxy-5-oxopentyl)-L-glutamine] + NADP+ + phosphate <=> [amino-group_carrier_protein]-C-terminal-{N-[1-carboxy-5-oxo-5-(phosphooxy)pentyl]-L-glutamine} + NADPH + H+
|
1.2.1.103
[amino-group carrier protein]-6-phospho-L-2-aminoadipate reductase
|
–
|
|
MetaCyc:
RXN-5183
|
|
|
|
homoisocitrate <=> (Z)-but-1-ene-1,2,4-tricarboxylate + H2O
|
4.2.1.114
methanogen homoaconitase
4.2.1.36
homoaconitate hydratase
|
–
–
|
|
BRENDA:
BR416
KEGG:
R04371
MetaCyc:
HOMOACONITATE-HYDRATASE-RXN
SABIO-RK:
4067
|
|
|
|
(R)-2-hydroxybutane-1,2,4-tricarboxylate <=> (Z)-but-1-ene-1,2,4-tricarboxylate + H2O
|
4.2.1
4.2.1.114
methanogen homoaconitase
4.2.1.36
homoaconitate hydratase
|
–
–
–
|
|
BRENDA:
BR49014;
BS1972
KEGG:
R03444
MetaCyc:
RXN3O-1983
SABIO-RK:
3238
|
|
|
|
[amino-group_carrier_protein]-C-terminal-[N-(1,4-dicarboxybutyl)-L-glutamine] + ATP <=> [amino-group_carrier_protein]-C-terminal-{N-[1-carboxy-5-oxo-5-(phosphooxy)pentyl]-L-glutamine} + ADP
|
2.7.2.17
[amino-group carrier protein]-L-2-aminoadipate 6-kinase
|
–
|
|
MetaCyc:
RXN-5182
|
|
|
|
homoisocitrate + NAD+ <=> 2-oxoadipate + CO2 + NADH
|
1.1.1.286
isocitrate---homoisocitrate dehydrogenase
1.1.1.42
isocitrate dehydrogenase (NADP+)
1.1.1.87
homoisocitrate dehydrogenase
|
–
–
–
|
|
BRENDA:
BR48021
KEGG:
R01934
MetaCyc:
RXN-7970
SABIO-RK:
1988
|
|